The first time I saw this patient she was 22 years old. She is a college
student. It is worth noting she experienced a sledge accident three years before
the onset of any symptoms where she suffered a significant shock to her back,
but without any immediate consequences. Three years later, when she was 19 years
old, she made a banal ski fall and the falls were to repeat regularly in
connection with a weakness of the right leg. She was to have a full causal
record that remained negative. Her walking was to become more and more difficult
with a weakness in both legs, but predominately in the right leg. In order to
move around, she is more often obliged to use crutches (see video 1).
Video 1
Magnetic Stimulation and Results
This patient benefited from a large field transcranial magnetic stimulation at
1Hz and peripheral stimulation of the lower limbs at 3Hz. A significant but
incomplete improvement in walking disturbances was achieved. Stimulations had to
be repeated every two months and, despite this type of treatment, she developed,
two years ago, a second type of symptom in the form of very intense abnormal
movements of the upper limbs occurring many times on a daily basis (see video
2). The peripheral magnetic stimulation on the upper limbs and at the level of
the neck was able to significantly improve the abnormal movements that
disappeared after a few sessions.
Video 2
Comments
This patient presents several types of symptoms. The first symptoms, a type of
weakness in the lower limbs, occurred after a banal ski fall. It is possible
that the episode, somewhat traumatic, three years ago created an area of
fragility in certain networks of the motor control. Once again we acknowledge
the very high fragility of brain connectivity present in some people. An
ordinary traumatic physical episode lead to very disabling symptoms. During the
course of evolution, another symptom appeared of extremely intense abnormal
movements of the trunk, upper limbs and neck. This sequence confirms the
sometimes evolving nature of functional neurological disorders. Without magnetic
stimulation, she would probably have evolved towards the use of a wheelchair.
Abnormal Movements - Patient 2
Dominique Parain MD PhD
History
This 42-year-old patient, who has had fibromyalgia for several years, developed,
six months ago, in a brutal way, without any particular triggering factor,
abnormal movements that reach the four limbs, abdominal muscles, head and which
clearly predominate when standing without any associated balance disturbances.
This tremor appears daily by access that can last several hours (see video 1).
The various investigations came back negative and the recording of abnormal
movements concluded a functional tremor.
Video 1
Magnetic Stimulation and evolution
From the first unique peripheral stimulation session, diffused at 25 Hz on the
four limbs and the trunk, there was an immediate and total disappearance of the
tremor (see video 2). These tremors would reappear 15 days later, but of a very
punctual nature, whereas before they were on a daily and very prolonged. After
the second stimulation session, all tremors disappeared almost completely.
Video 2
Comments
Having a fibromyalgia, it is possible this patient has a certain dysfunction of
peripheral proprioceptive sensors located in the connective tissue that may be
the cause of these functional tremors (see TNF
page and
syndrome Ehlers Danlos). The stimulation of these sensors by high-frequency
peripheral magnetic stimulation had a dramatic and immediate effect on this
patient. She will almost completely prevent re-occurences. The symptoms are very
similar (in the form of more durable and frequent access) to the recently
attacks in the Medias of Angela Merkel's tremors, which are clearly functional in
origin (see video 3).